Imine hydroboration

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August undefined, 2024

Witryna29 mar 2024 · A series of strongly Lewis acidic cationic aluminium complexes, stabilized by β–diketiminate (BDI) ligands and free of Lewis bases, have been prepared as their B(C 6 F 5) 4 − salts. Their catalytic activity in imine hydrogenation depends strongly on the substituents in the BDI ligand. DFT calculations on the mechanism reveal two …

Iron-catalysed hydroboration of non-activated imines and …

Witryna3 kwi 2024 · The first catalytic inverse hydroboration of imines with N-heterocyclic carbene (NHC) boranes has been realized by means of cooperative organocatalysis and photocatalysis, providing a promising platform for promoting NHC-boryl radical chemistry under sustainable and radical-initiator-free conditions. The first catalytic inverse … Witryna8 lis 2024 · The first use of diazaphospholenes as chiral catalysts has been demonstrated with enantioselective imine hydroboration. A chiral diazaphospholene prepared in a … simipour bst

Catalyst‐Free and Solvent‐Free Facile Hydroboration of Imines

Witryna16 wrz 2024 · Imine hydroboration has perennially featured in notable reports while nitrile and carbodiimide hydroboration have gained attention recently. Initial developments in catalytic hydroboration of ... WitrynaHeterocyclic C-substituted imine was applied under the given conditions, providing boronated aniline 7n in 40 min. When introducing an ester group to C-phenyl of … Witryna7 wrz 2024 · An, D.K. Lithium bromide: An inexpensive and efﬁcient catalyst for imine hydroboration with pinacolborane at room temperature. RSC Adv. 2024 , 10 , 34421–34427. patent administrative litigation

Applications of catalysis in hydroboration of imines, nitriles, and ...

P-N Cooperative Borane Activation and Catalytic Hydroboration …

WitrynaHydroboration can be considered as one of the most powerful methods for reduction of various organic substrates such as aldehydes, ketones, imines, and nitriles under mild reaction conditions [1–3]. Witryna27 mar 2024 · Compound 1 catalyzed chemoselective reduction of esters in the presence of other reducible functional groups such as alkene, alkyne and nitro is shown. Magnesium amide complexes such as Mg{N(SiMe3)2}2 (1) xylLMgN(SiMe3)2·THF (2) [xylL = ArNC(NiPr2)NAr; (Ar = 2,6-Me2-C6H3)] and dippLMgN(SiMe3)2·THF (3) … similitude unitary groupWitryna15 cze 2024 · A final comment on imine hydroboration is that in both cases 1 (73 % 0.5 h) offers marginally less reactivity than 3 (80 % 0.5 h). This difference may describe a subtle alkyl versus amido effect, whereby the replacement of one TMP anion for an i Bu anion imparts greater nucleophilicity onto the hydride, priming it for addition across the ... similitudes indirectes

"WitrynaWe report the use of a cyclic carbodiphosphorane catalyst for ketone and imine hydroboration reactions. Ketone hydroboration reactions are particularly rapid, typically reaching completion within 15 min using a 1 mol % catalyst loading at 25 °C. To our knowledge, this represents the first use of a carbodiphosphorane as an … " - Imine hydroboration

Imine hydroboration

Insights into LiAlH4 Catalyzed Imine Hydrogenation

Witryna11 sty 2024 · Boron Lewis acid-catalyzed and catalyst-free hydroboration reactions of imines are attractive due to the mild reaction conditions. In this work, the mechanistic … Witrynaimine hydroboration reveals a ﬁrst-order dependence on catalyst concentration. Both HBpin and 4-ﬂuorophenyl-N-phenylmethanimine (1b) appear to exhibit saturation …

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Witryna13 lut 2024 · Amines also promote imine reduction in certain cases, raising the possibility of a slow autocatalytic reaction. The ability of water or other protic impurities to promote the reduction of imines with pinacolborane represents an important identification of a potential source of background reaction in catalyzed reductions of imines. ... Witryna8 lis 2024 · The first use of diazaphospholenes as chiral catalysts has been demonstrated with enantioselective imine hydroboration. A chiral diazaphospholene prepared in a …

WitrynaHydroboration of nitriles and imines mediated by main‐group metal Mg under solvent‐free conditions has been reported. Simple ethoxymagnesium chloride (EtOMgCl) was found to be an effective promoter of nitrile and imine hydroboration at room temperature. The selective reduction of nitriles over alkenes and alkynes and … Witryna11 sty 2024 · Boron Lewis acid-catalyzed and catalyst-free hydroboration reactions of imines are attractive due to the mild reaction conditions. In this work, the mechanistic details of the hydroboration reactions of two different kinds of imines with pinacolborane (HBpin) are investigated by combining density functional theory calculations and …

Witrynacatalyst for imine hydroboration with pinacolborane at room temperature† Hanbi Kim, Hyun Tae Kim, Ji Hye Lee, Hyonseok Hwang and Duk Keun An * An eﬃcient protocol … Witryna11 sty 2024 · Detailed DFT calculations and experiments were performed to study the hydroboration mechanisms of two different kinds of imines. Our results revealed that …

Witryna19 cze 2024 · The rarely used boron Lewis acid tris[3,5-bis(trifluoromethyl)phenyl]borane (BArF3) is found to be an excellent catalyst for metal-free hydroboration of imines. In …

Witryna26 kwi 2024 · Consequently, catalytic hydroboration of a variety of imine substrates can be realized with 1 as the catalyst and HBpin as the terminal reagent. A mechanistic … similitudes entre spss y excelWitryna16 gru 2024 · We report the use of a cyclic carbodiphosphorane catalyst for ketone and imine hydroboration reactions. Ketone hydroboration reactions are particularly … patent clerk definitionWitryna1 sie 2024 · For the catalyst- and solvent-free hydroboration reaction of imine, N -benzylideneaniline, our calculations and experimental studies indicate that this … simimons hvac suppliesWitrynaThe catalytic dehydrocoupling of amine–boranes has recently received a great deal of attention due to its potential in hydrogen storage applications. The use of aluminum catalysts for this transformation would provide an additional cost-effective and sustainable approach towards the hydrogen economy. Herein, we report the use of … simi power plus para que sirveWitryna23 lut 2024 · We describe a simple and efficient procedure for nucleophilic borylation of imines in the absence of a photoredox catalyst. Visible light irradiation of an … patente api deudaWitryna1 gru 2007 · Magnesium catalysis of imine hydroboration. Merle Arrowsmith, M. Hill, G. Kociok‐Köhn; Chemistry. Chemistry. 2013; ... rate-determining process occurs at an isolated magnesium center and requires the presence of two molecules of the imine substrate for effective turnover, and this latter observation is rationalized as a … simiq syracuseWitryna1 wrz 2024 · LiAlH 4 catalysis: A combined experimental and theoretical investigation on LiAlH 4 catalyzed imine hydrogenation reveals mechanistic details as well as metal … patentes arm