Cisplatin electrolyte abnormalities

Author: pwkg

August undefined, 2024

WebCisplatin causes hypomagnesemia in a dose-dependent fashion and affects up to 90% of patients if no preventive measures are taken ... Hypomagnesemia is the most common electrolyte abnormality related to chronic alcohol abuse and affects as many as 30% of alcohol-dependent patients. 148, ... WebSep 15, 2024 · Cisplatin's side effects primarily include nephrotoxicity, gastrointestinal toxicity, neurotoxicity and ototoxicity. Cardiotoxicity is generally not defined as a side …

Cisplatin: Package Insert - Drugs.com

WebSep 1, 2024 · Cisplatin for injection can cause severe hypersensitivity reactions, including anaphylaxis and death. Manifestations have included facial edema, wheezing, … Web5.3 Electrolyte and Metabolic Abnormalities In addition to causing hyperkalemia, spironolactone tablets can cause hyponatremia, hypomagnesemia, hypocalcemia, hypochloremic alkalosis, and hyperglycemia. Asymptomatic hyperuricemia can occur and rarely gout is precipitated. Monitor serum electrolytes, uric acid and blood glucose … five can salsa

Chapter 5: Electrolyte and Acid Base Disorders in Malignancy

WebNov 1, 2024 · Special attention needs to be paid to electrolyte disturbances, which should be particularly considered when administering high doses of cisplatin [19]. The most common electrolyte disorder is ... WebApr 12, 2024 · In cancer patients, electrolyte disorders are frequent due to tubular functional abnormalities related to chemotherapeutic drugs, the TLS and the impaired secretion of antidiuretic hormone ... As previously described, also the cisplatin can induce electrolyte imbalances. In this case, the standard approach to avoid cisplatin-induced ... WebMay 19, 2024 · Electrolyte disorders are also related to cisplatin-induced DNA damage of thiazide-sensitive sodium-chloride co-transporter genes and to the apoptosis of distal tubule cells . Cisplatin treatment … canine swimming facilities

Electrolyte disorders with platinum-based chemotherapy …

Cisplatin electrolyte abnormalities

Electrolyte disorders in cancer patients: a systematic review

WebJun 8, 2024 · Cisplatin injection can cause dose-related peripheral neuropathy that becomes more severe with repeated courses of the drug. Neurologic symptoms have … WebJun 8, 2024 · Acute overdosage with cisplatin injection may result in renal failure, hepatic failure, hearing loss, ocular toxicity, myelosuppression, nausea and vomiting, and neuritis.

Did you know?

WebFeb 16, 2024 · Common side effects of cisplatin may include: hearing problems; kidney problems; numbness or tingling; nausea, vomiting; or. bone marrow suppression. This is … Web• Hypomagnesemia and Accompanying Electrolyte Abnormalities: Monitor during treatment and for at least 8 weeks following the completion. Replete electrolytes as necessary. (5.6) ... and Cisplatin . 5.6 Hypomagnesemia and Accompanying Electrolyte Abnormalities . 5.7 Increased Tumor Progression, Increased Mortality, or Lack ...

WebHypomagnesemia may cause nausea, vomiting, sleepiness, weakness, personality changes, muscle spasms, tremors, and loss of appetite. If severe, hypomagnesemia can cause seizures Seizure Disorders In seizure disorders, the brain's electrical activity is periodically disturbed, resulting in some degree of temporary brain dysfunction. Many …

WebCisplatin can cause increased magnesium losses by the kidneys as well as generalized decrease in kidney function. Magnesium loses can be severe and persist despite discontinuation of cisplatin. Discontinuation of cisplatin is still recommended if signs of renal toxicity occur during therapy. Table Causes of Hypomagnesemia WebJul 20, 2024 · Electrolyte abnormalities that converge on hypomagnesemia and serve as important diagnostic clues to its presence include …

WebJun 10, 2024 · However, cisplatin is known to cause a variety of adverse effects (such as nausea and vomiting, renal insufficiency, electrolyte abnormalities, myelosuppression, ototoxicity, peripheral neuropathy, hepatotoxicity, and retinopathy) than other chemotherapy regimens. Diarrhea, pancreatitis, seizures, and respiratory failure have also been reported.

WebMay 18, 2024 · Amphotericin B is used in the treatment of often life-threatening fungal infections (see "Pharmacology of amphotericin B"). Impaired kidney function is a … five canyons hoaWebDec 9, 2024 · Electrolyte disorders are very common conditions in cancer patients. They mainly concern changes in serum sodium, potassium, calcium, and magnesium levels. In most cases, these alterations are asymptomatic and therefore not always taken into consideration in clinical practice. canine swollen lymph node causesWebCisplatin is a coordinate metal complex with significant antineoplastic activity and various effects, including acute anc chronic renal insufficiency and renal magnesium … five canyons open spaceWebSep 18, 2024 · NCBI Bookshelf five can dump soup recipeWebmay drive unique electrolyte disorders in different malignancies. In the next sections, the clinical fea-tures, pathophysiology, and treatment of the most … five canyons recreation centerWebJun 24, 2024 · The most common electrolyte abnormalities were hypomagnesemia (88.9%, Vancouver) and hypophosphatemia (24.2%, Mexico City). ... Since nephrotoxicity is commonly found in cisplatin-treated children, electrolyte abnormalities can also help in understanding a patient’s kidney function, especially in the early stage of cisplatin … five canyons rec centerWebManufacturer advises cisplatin requires intensive intravenous hydration and treatment may be complicated by severe nausea and vomiting. ... Side-effects Side-effects For cisplatin. Common or very common. Anaemia; arrhythmias; bone marrow failure; electrolyte imbalance; extravasation necrosis; fever; leucopenia; nephrotoxicity (dose-related and ... five canonical victims of jack the ripper