Webcancer patients [18]. Furthermore, circANKS1B also acts as a sponge of miR-149 to promote colorectal cancer cell migration and invasion [19]. Analogously, circANKS1B … WebD L, R Y, L Y, D W, X Z, Y S: circANKS1B regulates FOXM1 expression and promotes cell migration and invasion by functioning as a sponge of the miR-149 in colorectal cancer. OncoTargets and therapy 2024, 12(undefined):4065-4073.
CircRNAs: role in human diseases and potential use as biomarkers
WebBackground: A growing number of studies indicate that circular RNAs (circRNAs) play critical roles in human diseases, and show great potential as biomarkers and therapeutic … WebFeb 11, 2024 · Similarly, enrichment of circANKS1B in HPV-positive cervical cancer exosomes may play a role in influencing cellular migration and invasion. circANKS1B increases the expression of transcription factor USF1, which upregulates TGF-β1 expression resulting in activated TGF-β1/Smad signaling and EMT in breast cancer . easiest way to invest in bitcoin uk
National Center for Biotechnology Information
WebNov 19, 2024 · Increased circANKS1B expression was closely associated with lymph node metastasis and advanced clinical stage and served as an independent risk factor for overall survival of breast cancer patients. Functional studies revealed that circANKS1B promoted breast cancer invasion and metastasis both in vitro and in vivo by inducing epithelial-to ... WebMay 10, 2024 · CircANKS1B used miR-148a-3p and miR-152-3p to intensify the expression of the transcription factor USF1, consequently activating the TGF-β1/Smad regulatory circuit to increase EMT. Studies declared that circNR3C2 [ 107 ], hsa_circ_0006220, circTADA2A-E6 and circITCH had a negative impression on the regulation of metastasis through … WebNov 19, 2024 · CircANKS1B (a circRNA originated from exons 5 to 8 of the ANKS1B gene, hsa_circ_0007294) was identified by RNA-sequencing and validated by qRT-PCR and … easiest way to invest in top cryptocurrencies