Chloromethyl isopropyl carbonate synthesis
WebUNII - 6S8MF45ZHW CHLOROMETHYL ISOPROPYL CARBONATE UNII: 6S8MF45ZHW Formula: C5H9ClO3 Preferred Substance Name: CHLOROMETHYL ISOPROPYL CARBONATE InChIKey: JHYNXXBAHWPABC-UHFFFAOYSA-N... WebFeb 18, 2014 · Chloromethyl isopropyl carbonate preparation method. The present invention belongs to the field of antiviral chemical drugs, and particularly relates to a …
Chloromethyl isopropyl carbonate synthesis
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Webthe intermediate, which is isolated and purified, in the multi-step synthesis process of emtricitabine. The structure and stereochemistry of this intermediate has been critically ... solution, chloromethyl isopropyl carbonate content (GC) and residual solvents (GC). The limits of the related substances are in agreement ICH Q3A requirements. The ... Weband then esterified with chloromethyl isopropyl carbonate (CMIC, 9) to yield crude tenofovir disoproxil (TD, 10). Treatment of crude TD with fumaric acid gives crystalline TDF in a 13% overall yield. Scheme 1. Synthetic Strategies for tenofovir disoproxil fumarate and tenofovir alafenamide fumarate.
WebMar 28, 2024 · Report predicts that the global Chloromethyl Isopropyl Carbonate (CAS 35180-01-9) market size will expected to achieve a constant upswing in 2028 with a growing CAGR from 2024-2028.
WebAryl-substituted bridged or fused diamine compounds, pharmaceutical compositions containing them, and methods of using the compounds and the pharmaceutical compositions for leukot WebBuy Chloromethyl isopropyl carbonate USP compendial standard (CAS 35180-01-9) to determine strength, quality, purity and identity in your USP-NF monograph tests and …
WebChloromethyl chloroformate was used as key reactant in the synthesis of: novel aminocarbonyloxymethyl esters of diclofenac and flufenamic acid [ 1] highly water-soluble monomethoxypoly (ethyleneglycol) prodrugs of cyclosporin A [ 2] series of 3-acyloxymethyloxycarbonyl-1-aryl-3-methyltriazenes [ 3] Packaging 10, 50 mL in glass bottle
WebChloromethyl Isopropyl Carbonate (CMIC) CAS No.: 35180-01-9. CMIC is Colourless and transparent liquid. It is used Anti-AIDS and hepatitis B drugs tenofovir and intermediate in organic synthesis. Hexamethyl Disilazane (HMDS/HMDZ) - CAS No. : 999-97-3. Organosilicon compound with the formula O[Si(CH3)3]2. This volatile colourless liquid is … harry potter band 1 englischWebChloromethyl Isopropyl Carbonate (CMIC) CAS No.: 35180-01-9 CMIC is Colourless and transparent liquid. It is used Anti-AIDS and hepatitis B drugs tenofovir and intermediate … charles and marguliesWebMar 15, 2024 · This molecule is used in the preparation of tenofovir disoproxil fumarate (TDF), a common active pharmaceutical ingredient (API) used in the treatment of … charles and marie robertson foundationWebProduct name : Chloromethyl Isopropyl Carbonate Product Number : 28997 CAS-No. : 35180-01-9 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Manufacture of substances 1.3 Details of the supplier of the safety data sheet Company : Capot Chemical Co.,Ltd. charles and marie kelly columbus nyWebB. 1-Methoxymethyl-1-phenylethane.The reaction flask containing a toluene solution of chloromethyl methyl ether (250 mmol, 1.5 equiv) prepared above is immersed in a cold water bath and the contents cooled to 5–10 °C. α-Phenethyl alcohol (20 mL, 166 mmol, 1 equiv) is charged to the addition funnel and added in one portion (Note 11). ... charles and marjorie holloway foundationWebTo a stirred suspension of PMPA (26 mmol) in DMF (100 mL) at 50°C triethylamine (TEA) (77.8 mmol) was added. The reaction mixture became homogeneous and chloromethyl … charles and mary bangleWebJan 20, 2024 · CHLOROMETHYL ISOPROPYL CARBONATE (CARBON) Synonym. Carbonic Acid Chloromethyl Isopropyl Ester. Product Code. 0603001. CAS # 35180‐01‐9. Molecular Formula. C5H9ClO3. Molecular Weight. 152.57. MDL No. MFCD07375443. Pack Size Description Price Quantity; 2.5kg: Available to ship on January 20, 2024 harry potter ball with wings